cGAS/cGAMP/STING signal propagation in the tumor microenvironment: Key role for myeloid cells in antitumor immunity.
Authors: Mekers, Vera E and Kho, Vera M and Ansems, Marleen and Adema, Gosse J
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology (2022): 158-167
Novel Poxin Stable cGAMP-Derivatives Are Remarkable STING Agonists.
Authors: Stazzoni, Samuele and Böhmer, Daniel F R and Hernichel, Fabian and Özdemir, Dilara and Pappa, Aikaterini and Drexler, David and Bauernfried, Stefan and Witte, Gregor and Wagner, Mirko and Veth, Simon and Hopfner, Karl-Peter and Hornung, Veit and König, Lars M and Carell, Thomas
Journal: Angewandte Chemie (International ed. in English) (2022): e202207175
Discovery of Non-Nucleotide Small-Molecule STING Agonists via Chemotype Hybridization.
Authors: Cherney, Emily C and Zhang, Liping and Lo, Julian and Huynh, Tram and Wei, Donna and Ahuja, Vijay and Quesnelle, Claude and Schieven, Gary L and Futran, Alan and Locke, Gregory A and Lin, Zeyu and Monereau, Laura and Chaudhry, Charu and Blum, Jordan and Li, Sha and Fereshteh, Mark and Li-Wang, Bifang and Gangwar, Sanjeev and Pan, Chin and Chong, Colin and Zhu, Xiao and Posy, Shana L and Sack, John S and Zhang, Ping and Ruzanov, Max and Harner, Mary and Akhtar, Fahad and Schroeder, Gretchen M and Vite, Gregory and Fink, Brian
Journal: Journal of medicinal chemistry (2022): 3518-3538